The plants are grown from seed, and it is customary, in tropical countries, to sow several crops each season to insure against failure and that collecting may be less interrupted, Plants of the spring sowing flower in July. The pods do not all mature at the same time; this, coupled with the sowing of several crops at intervals of four to six months, makes the work of collect almost continuous. Before the pods are fully developed they are incised horizontally or vertically with a knife. Generally a special knife with two and three parallel blades is used. The blades of the knife are repeatedly moistened with saliva to prevent the poppy juice from adhering to them.

The incisions must not extend through the walls of the capsule, as some of the juice would escape into the interior and be lost. As soon as the incisions are made a milky sap exudes, which gradually thickens, due to the evaporation of moisture, and becomes darker in color. The following day the sticky, now dark-brown juice, is scraped off and smeared on a poppy leaf held in the left hand; more and more juice is added until a goodly sized lump is collected. These sticky, ill-smelling masses of opium are now placed in a shaded place to dry. The entire process of incising and collecting as carried on by the Orientals is exceedingly uncleanly. To the nasty habit of moistening the knife-blade with saliva is supplemented the filth of unwashed hands and the sand and dirt of the poppy leaves, which are added from time to time to form a new support for the juice as it is removed from the knife. In scraping the gum considerable epidermal tissue is also included. Each lump of gum opium contains therefore a mixture of spittle, the filth of dirty hands, poppy leaves, sand, and dust. In addition to that many collectors adulterate the gum opium with a great variety of substances. Dioscorides mentions the fact that even in those remote times adulteration of opium was practiced, such substances as lard, syrup, juice of lactuca, and glancium being added. Modern collectors and dealers adulterate opium with sand, pebbles, clay, lead, flour, starch, licorice, chicory, gum arabic and other gums, figs, pounded poppy capsules, an excessive quantity of poppy leaves and other leaves, etc. After collecting and drying the peasants carry the gum opium to the market places, where they are met by the buyers and merchants, who inspect the wares and fix a price very advantageous to themselves.

The present trade in opium is something enormous, especially in India, China, and Asia Minor.

To the credit of the Chinese and the discredit of the English it must be said that in 1793 the former strenuously objected to the introduction of opium traffic by the latter. This opposition by the Chinese government culminated in the "Opium War," which led to the treaty of Nanking in 1842, giving the English the authority to introduce opium into China as a staple article of commerce. The reason that Chinese officials objected to the introduction of opium was because they recognized the fact that the inhabitants very readily acquired the habit of smoking opium. In spite of the most severe government edicts the habit spread very rapidly after the treaty referred to.

Gum opium contains active principles (alkaloids), to which it owes its peculiar stimulating, soporific, and pain relieving powers. Of these alkaloids, of which there are about nineteen, morphine and codeine are undoubtedly the most important. The properties of gum opium represent therefore the collective properties of all of the alkaloids and are similar to the properties of the predominating alkaloids just mentioned.

Physicians generally agree that opium is the most important of medicines. Properly used it is certainly a great boon to mankind, for which there is no substitute, but, like all great blessings, it has its abuses. It is the most effective remedy for the relief of pains and spasms of all kinds. It will produce calm and sleep where everything else has failed. It finds a use in all diseases and ailments accompanied by severe pain, in delirium, rheumatic and neuralgic troubles, in dysentery, etc. It may be applied externally to abraded surfaces, to ulcers and inflamed tissues for the relief of pain. The value of opium does not lie so much in its direct curative powers as in its sedative and quieting effects upon diseased organs, which tends to hasten or bring about the healing or recuperating process. In some diseases the physician refrains from giving opium, as in fully developed pneumonia, since the quieting effect would diminish the efforts on the part of the patient to get rid of the inflammatory products accumulating in the air vesicles and finer bronchial tubes. In fact, the soothing effect is too often mistaken for a curative effect and the patient is neglected. The Roman habit of feeding children pap mixed with poppy juice was a pernicious one. Many modern mothers give their sick and crying infants "soothing syrups," most, if not all, of which contain opium in some form, as tincture of opium and paregoric. Too often the poor, overworked mother, who cannot afford to consult a physician, will purchase a bottle of "soothing syrup" or "cough remedy" for her child because she knows it produces a quieting effect, which is mistaken for a cure, when in reality the incipient symptoms are only masked. Only a reliable physician should be permitted to prescribe opium in any form.